Pharmacotherapy and psychotherapy in the treatment of psychiatric disturbances

The type of treatment that most psychiatric disturbances receive at present is a mixture of pharmacotherapy and psychotherapy, following the principle that mental functions are the result of the activities of brain machinery subsequent to the interaction between individuals and their external enviro nment. We now know the molecular mechanism of action of several psychoactiv e drugs but have scant understanding of the correlation between molecular e vents and mental function. As for psychotherapy, we know that it may have b eneficial effects on patients' behavior but ignore the issue of whether thi s has any correlate at molecular level. A black box still exists between dr ugs, neurotransmitters, receptors, and the higher brain functions defined a s anxiety, emotion, arousal, etc. Yet mental treatments imply a therapeutic method in which the blend of drugs and words administered to patients is d etermined by the choice of the therapist and by the specific pathology reco gnized through clinical diagnosis. In this epistemologically confused situa tion, the pharmaceutical industry is playing a major role in orientating th e medical profession towards the use of more and more powerful neurotropic substances with very detailed molecular actions and plenty of side-effects. Nevertheless, the use of psychotropic drugs has allowed the opening of the psychiatric hospitals and the 'liberation' of millions of psychiatric pati ents. This beneficial effect is counterbalanced by the dependency of millions of individuals on psychotropic drugs. The situation leads to a number of questions relative to the possible links among words, molecules, and behaviors. The present paper illustrates a theoretical model which can be used to comp are and contrast psychotherapy and pharmacotherapy.