We diagnosed 60 cases of midbrain tumours by MRI between 1993 to 1997. Ther
e were 39 males and 21 females, aged 2-64 years, mean 25.6 years. We found
38 patients with true intramedullary midbrain tumours, 11 predominantly in
the tectum, 20 in the tegmentum and 7 with a downward extension to the pens
; there were 7 within the cerebral aqueduct. There were 22 patients with in
filtrating midbrain tumours extending from adjacent structures, 11 cases ea
ch from the thalamus and pineal region. All patients received surgical trea
tment. Gross total resection was achieved in 42 cases. subtotal (> 75 %) re
section in 18. Pathological diagnoses included 16 low-grade and 15 high-gra
de astrocytomas; 5 oligodendro-astrocytomas; 2 ependymomas; 11 glioblastoma
s; and 11 pineal parenchymal or germ-cell tumours. Midbrain tumours are a h
eterogeneous group of neoplasms, with wide variation in clinical and MRI fe
atures, related to the site and type of tumour. MRI not only allows precise
analysis of their growth pattern, but also can lead to a correct preoperat
ive diagnosis in the majority of cases.