High-intensity basal ganglia lesions on T1-weighted images in two toddlerswith elevated blood manganese with portosystemic shunts

Authors
Ihara, K Hijii, T Kuromaru, R Ariyoshi, M Kira, R Fukushige, J Hara, T
Citation
K. Ihara et al., High-intensity basal ganglia lesions on T1-weighted images in two toddlerswith elevated blood manganese with portosystemic shunts, NEURORADIOL, 41(3), 1999, pp. 195-198
Citations number
25
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEURORADIOLOGY
ISSN journal
00283940 → ACNP
Volume
41
Issue
3
Year of publication
1999
Pages
195 - 198
Database
ISI
SICI code
0028-3940(199903)41:3<195:HBGLOT>2.0.ZU;2-H
Abstract
We report two toddlers with portosystemic shunts who had symmetrical high-s ignal globus pallidus lesions on T1- but not T2-weighted MRI, and measureme nt of whole blood manganese at 2 years of age. These cases suggest that por tosystemic shunts can cause elevation of blood manganese and result in mang anese accumulation in the globus pallidus, causing high signal on T1-weight ed images even in asymptomatic toddlers.