INTERACTION BETWEEN EMBRYONIC NERVOUS-TIS SUE AND GLIOMA DURING THEIRSIMULTANEOUS CULTIVATION AND TRANSPLANTATION INTO BRAIN

The influence of embryonic nervous tissue (ENT) grafts on glioma 101.8 development was investigated. It was shown that simultaneous transpla ntation of tumor and ENT fragments did not stimulate glioma developmen t, but sometimes inhibited its growth. During simultaneous cultivation of the tumor and embryonal rat brain tissues the lysis of glioma cell s was observed, as well as the reduction of their migration and prolif erative properties. As the implantation of tumor cells in the brain of rat embryones occured, the death of glioma cells in the absense of vi sual damage of embryonal brain tissues was recorded. These findings al low to suggest the availability of antitumor properties in ENT.