The opium poppy and the coca leaf offer useful perspectives on the current
controversies over medical marijuana. In both cases, purified synthetic ana
logues of biologically active components of ancient folk remedies have beco
me medical mainstays without undermining efforts to reduce nonmedical drug
use. A decade ago, a campaign strove to legalize heroin for the compassiona
te treatment of pain in terminally ill patients. Like the current campaign
to legalize medical marijuana, many well-meaning people supported this effo
rt. The campaign for medical heroin was stopped by science when double-blin
d studies showed that heroin offered no benefits over the standard opioid a
nalgesics in the treatment of severe cancer pain.
Scientific medicine requires purified chemicals in carefully controlled dos
es without contaminating toxic substances. That a doctor would one day writ
e a prescription for leaves to be burned is unimaginable. The Controlled Su
bstances Act and international treaties limit the use of abused drugs or me
dicines. In contrast to smoked marijuana, specific chemicals in marijuana o
r, more likely, synthetic analogues, may prove to be of benefit to some pat
ients with specific illnesses. Most opponents of medical use of smoked mari
juana are not hostile to the medical use of purified synthetic analogues or
even synthetic tetrahydrocannabinol (THC), which has been available in the
United States for prescription by any licensed doctor since 1985. In contr
ast, most supporters of smoked marijuana are hostile to the use of purified
chemicals from marijuana, insisting that only smoked marijuana leaves be u
sed as "'medicine," revealing clearly that their motivation is not scientif
ic medicine but the back door legalization of marijuana.