Inhibitory effect of green and black tea on tumor growth

Authors
Conney, AH Lu, YP Lou, YR Xie, JG Huang, MT
Citation
Ah. Conney et al., Inhibitory effect of green and black tea on tumor growth, P SOC EXP M, 220(4), 1999, pp. 229-233
Citations number
11
Categorie Soggetti
Medical Research General Topics
Journal title
PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE
ISSN journal
00379727 → ACNP
Volume
220
Issue
4
Year of publication
1999
Pages
229 - 233
Database
ISI
SICI code
0037-9727(199904)220:4<229:IEOGAB>2.0.ZU;2-1
Abstract
The administration of green tea, black tea, or (-)-epigallocatechin gallate inhibited the growth of established nonmalignant and malignant tumors in t umor-bearing mice. In experiments with black tea, we found that its oral ad ministration inhibited DNA synthesis and enhanced apoptosis in both nonmali gnant and malignant tumors in tumor-bearing mice.