Solid phase acylation of phosphonoacetates: Synthesis of beta-keto phosphonates from polymer bound phosphonoacetate

Authors
Kim, DY Suh, KH
Citation
Dy. Kim et Kh. Suh, Solid phase acylation of phosphonoacetates: Synthesis of beta-keto phosphonates from polymer bound phosphonoacetate, SYN COMMUN, 29(8), 1999, pp. 1271-1275
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
29
Issue
8
Year of publication
1999
Pages
1271 - 1275
Database
ISI
SICI code
0039-7911(1999)29:8<1271:SPAOPS>2.0.ZU;2-T
Abstract
Solid phase synthesis of phase synthesis of P-keto phosphonates, via acylat ion reaction of polymer bound phosphoacetate with carboxylic acid chlorides in the presence of magnesium chloride-triethylamine followed by cleavage o f resin with concomitant decarboxylation, is described.