Alcohol intake contributes to energy balance. Chronic and moderate alcohol
consumption (i. e. 20-40 g/day) plus a high fat intake (i. e. > 40% of ener
gy intake) fat-or a positive energy balance and thus weight gain. By contra
st a high alcohol intake (i. e. > 20% of energy intake) may lead to malnutr
ition depending on the concomitant nutrient intake. It is evident that alco
hol cannot be considered as an empty calorie. En Energy wasting mechanisms,
which have been proposed by some authors, are unlikely to contribute to en
ergy balance in healthy subjects.
Our present knowledge on the energetic value of alcohol mainly depend on ph
ysiologic data based on the measurements of energy and substrate balances.
By contrast epidemiologic data on the effect of alcohol intake on body weig
ht are contradictory. This is explained by the limitations of epidemiologic
al studies as well as by the possible contributions of other life style-rel
ated factors.
It is evident that many studies on the effect of alcohol on body weight are
uncontrolled studies. It is surprising that although 100 years of research
have gone in this area we still have no definite answer to the question.