DETERMINATION OF VINYLMAGNESIUM HALIDE REAGENTS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AFTER REACTION WITH ANTHRALDEHYDE

A reversed-phase HPLC method has been developed for the determination of vinylmagnesium chloride and vinylmagnesium bromide, based on the as say of 1-(9-anthryl)propen-2-ol, the product in the reaction between a vinylmagnesium halide and 9-anthraldehyde. The HPLC system with UV de tection and an acetonitrile-water mobile phase containing phosphoric a cid buffer was used for the separation and quantification of the react ion product after extraction, The method-is selective for 1-(9-anthryl )propen-2-ol and linear response was established at 227 nm in the 0.00 2 to 0.5 mg ml(-1) concentration range, Vinylmagnesium halide concentr ation was calculated by using benzophenone as an external reference st andard to standardize the response of authentic 1-(9-anthryl)propen-2- ol.