INTERACTION OF SHORT OLIGONUCLEOTIDE DERI VATIVES WITH NUCLEIC-ACIDS .3. PHOTOMODIFICATION OF DNA TARGETS USING TANDEMS OF SHORT OLIGONUCLEOTIDE DERIVATIVES
Dr. Tabatadze et al., INTERACTION OF SHORT OLIGONUCLEOTIDE DERI VATIVES WITH NUCLEIC-ACIDS .3. PHOTOMODIFICATION OF DNA TARGETS USING TANDEMS OF SHORT OLIGONUCLEOTIDE DERIVATIVES, Bioorganiceskaa himia, 23(8), 1997, pp. 642-647
High efficiency was demonstrated for the photomodification of a DNA ta
rget by a 5'-p-azidotetrafluorobenzoyl reagent based on a tetranucleot
ide and its 3'-phosphoestrone ester in the presence of a pair of flank
ing effecters. These effecters are oligonucleotide derivatives with N-
(2-hydroxyethyl)phenazinium groups or those connected to cholesterol r
esidues at the terminal phosphates.