A CONVENIENT ACYLATION PROCEDURE OF ALCOH OLS AND AMINES

The reaction of carboxylic acids with primary and secondary alcohols i n the presence of aromatic sulfochlorides (mesitylenesulfonyl chloride and 2,4,6-triisopropylbenzenesulfonyl chloride) or aromatic sulfotetr azoles (mesytilenesulfonyl tetrazolide and 2,4,6-triisopropylbenzenesu lfonyl tetrazolide) and usual acylation catalysts was shown to be a co nvenient procedure for the synthesis of esters. Reaction of carboxylic acids with primary aliphatic or aromatic amines in the presence of th e same tetrazolides and catalysts is a useful procedure for the synthe sis of amides. Syntheses of twenty compounds are presented as examples .