ENANTIOSELECTIVE CATALYSIS .23. AMINOALCOHOL ASSISTED DECARBOXYLATIONOF 2-CARBOXY-2-METHYL-1-TETRALONE LEADING TO ENANTIOENRICHED 2-METHYL-1-TETRALONE

Authors
HENIN F MUZART J NEDJMA M RAU H
Citation
F. Henin et al., ENANTIOSELECTIVE CATALYSIS .23. AMINOALCOHOL ASSISTED DECARBOXYLATIONOF 2-CARBOXY-2-METHYL-1-TETRALONE LEADING TO ENANTIOENRICHED 2-METHYL-1-TETRALONE, Monatshefte fuer Chemie, 128(11), 1997, pp. 1181-1188
Citations number
24
Categorie Soggetti
Chemistry
Journal title
Monatshefte fuer Chemie → ACNP
ISSN journal
00269247
Volume
128
Issue
11
Year of publication
1997
Pages
1181 - 1188
Database
ISI
SICI code
0026-9247(1997)128:11<1181:EC.AAD>2.0.ZU;2-D
Abstract
Catalytic amounts of enantiopure aminoalcohols assist the decarboxylat ion of 2-carboxy-2-methyl-1-tetralone to 2-methyl-1-tetralone affordin g enantiomeric excesses of up to 35%. A rapid screening of the efficie ncy of various potential inductors of enantioselectivity has been carr ied out using circular dichroism spectroscopy.