CHLOROMETHYL(DIMETHYL)SULFONIUM TRIFLUOROMETHANESULFONATE - THE REAGENT FOR PREPARATION OF ACETALS OF 2-HYDROXYALDEHYDES FROM KETONES UNDERBASIC CONDITIONS

Authors
KACZMARCZYK G JONCZYK A
Citation
G. Kaczmarczyk et A. Jonczyk, CHLOROMETHYL(DIMETHYL)SULFONIUM TRIFLUOROMETHANESULFONATE - THE REAGENT FOR PREPARATION OF ACETALS OF 2-HYDROXYALDEHYDES FROM KETONES UNDERBASIC CONDITIONS, Synlett, (8), 1997, pp. 921
Citations number
12
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
8
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):8<921:CT-TR>2.0.ZU;2-Z
Abstract
2-Hydroxyaldehydes dimethylacetals 5 are synthesized via reaction of c hloromethyl(dimethyl)sulfonium trifluoromethanesulfonate (1) with keto nes 2, carried out in the presence of sodium methoxide in methanol. Th e corresponding 2-chloro-(3a) or 2-dimethylsulfonium-oxirane (3b) are presumably transient intermediates.