STEREOSELECTIVE REDUCTION OF CONJUGATED HOMOPROPARGYLIC ALCOHOLS TO (E)-HOMOALLYLIC ALCOHOLS BY SODIUM BIS(2-METHOXYETHOXY) ALUMINUM-HYDRIDE

Authors
CROUSSE B ALAMI M LINSTRUMELLE G
Citation
B. Crousse et al., STEREOSELECTIVE REDUCTION OF CONJUGATED HOMOPROPARGYLIC ALCOHOLS TO (E)-HOMOALLYLIC ALCOHOLS BY SODIUM BIS(2-METHOXYETHOXY) ALUMINUM-HYDRIDE, Synlett, (8), 1997, pp. 992
Citations number
24
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
8
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):8<992:SROCHA>2.0.ZU;2-6
Abstract
The reduction of various conjugated homopropargylic alcohols with sodi um bis(2-methoxyethoxy) aluminium hydride (Red-Al(R)) in ether or THF is described. The reaction takes place cleanly and rapidly, under mild conditions, to give (E)-homoallylic alcohols stereoselectively in goo d isolated yields.