COINCIDENCE OF HUNTINGTON-DISEASE AND EPI LEPSY

We report on a patient suffering from epilepsy and severe personality changes. Huntington disease was diagnosed by molecular-biological Inve stigation. Clinical characteristics are discussed on the basis of mode rn concepts of the genetic mechanism. Neuroradiological investigation revealed marked cerebellar atrophy, while typical findings of Huntingt on disease, such as caudate nucleus volume loss, were lacking. The cer ebellar atrophy could be attributable either to long-term phenytoin-me dication or to the pathological process itself.