Aj. Hunter et Re. Bryant, LOWER RESPIRATORY-TRACT INFECTIONS IN ELDERLY PATIENTS WITH ASTHMA, Immunology and allergy clinics of North America, 17(4), 1997, pp. 671
Asthma continues to be a significant disorder for the geriatric popula
tion. Although aging and asthma itself may predispose individuals to m
ore severe and protracted infections, the organisms and course of infe
ctions in elderly individuals are more dependent upon associated comor
bidities and overall physiologic health, rather than any age of asthma
-associated immune deficiencies. Except for the recent association wit
h Chlamydia pneumoniae, and the known association with ABPA, the cause
s of pneumonia in the elderly asthmatic are similar to those occurring
in nonasthmatic elderly. This article reviews the effects of aging, n
utrition, and asthma on the host immune system, and the role of infect
ion in the pathogenesis and exacerbations of asthma. Additionally, the
authors review admission decision analysis in the elderly, concluding
with preventive and therapeutic strategies for the elderly patient wi
th pneumonia.