The optimal management of the multi-organ donor is critical to the suc
cessful outcome of transplantation. It is a complex challenge demandin
g careful attention to detail, and requiring a shift in emphasis, sinc
e the pathophysiological processes have far reaching effects which man
y clinicians do not see on a day-to-day basis. The optimal management
of haemodynamic and respiratory status is essential in order to maximi
se the yield of suitable thoracic donor organs, yet this process will
also improve the condition of other organs at the time of procurement
and thus enable prompt recovery of function following hepatic and rena
l transplantation. The process commences when a potential donor is ide
ntified, and is only complete after successful transplantation of all
possible organs. in order to achieve this end, a dedicated, multi-disc
iplinary team is necessary, consisting not only of medical staff, but
also support workers who organise logistics, and who play their own pa
rt in vital areas, such as transport of the donor team and organs. The
co-ordinator's role is pivotal in bringing together, in harmony, team
s from different centres. it is important to remember that the effort
of every person involved in the management and procurement of donor or
gans is primarily directed towards maximisation of the donor pool, and
that our main responsibility is to the recipients on our waiting list
s.