Patients with acute leukaemia may have spuriously low arterial oxygen
tensions (PaO2), The markedly increased numbers of white blood cells i
n these patients rapidly consume dissolved plasma oxygen resulting in
dramatically decreased PaO2 and calculated oxygen saturations. The cas
e history is reported of a patient with a white blood count of 191 000
/mm(3) in whom multiple arterial blood gas measurements documented hyp
oxaemia out of proportion to the clinical picture. Pulse oximetry was
used to confirm higher haemoglobin oxygen saturations and to establish
the spuriously low plasma oxygen tensions in this patient.