Tll. Carvalho et al., CHRONOLOGY OF ALVEOLAR HEALING FOLLOWING IMMEDIATE IMPLANTATION OF RICINUS-COMMUNIS POLYURETHANE RESIN - HISTOMETRIC ANALYSIS IN RATS, Journal of biomedical materials research, 37(4), 1997, pp. 449-452
The purpose of the present study was to determine whether granules of
Ricinus communis polyurethane resin implanted immediately after tooth
extraction interfere with the time course of alveolar wound healing in
rats. Progressive bone neoformation in parallel to a decrease in the
volume fraction of connective tissue was quantified by a histometric m
ethod 1, 2, 3, and 6 weeks after tooth extraction. In spite of the bio
compatible nature, the presence of polyurethane resin granules in the
cervical third led to a small (9-22%) but significant delay in bone fo
rmation in the middle and apical alveolar thirds from the second week
on, as compared to controls. (C) 1997 John Wiley & Sons, Inc.