Our surgical and functional experience with orthotopic bladder replace
ment in women is presented. Urethral support sparing cystectomy and th
e ileal neobladder as reservoir guarantee excellent continence in all
patients. Retention in 20% to 30% of patients is the critical issue, r
ather than the expected incontinence. The advent of orthotopic lower u
rinary tract reconstruction in women is a major achievement in the evo
lution of urinary diversion. With our increasing understanding of the
continence mechanism in women, and with increasing evidence that the f
emale urethra can be safely preserved after cystectomy, orthotopic low
er urinary tract reconstruction (by the ileal neobladder) can be offer
ed safely, not only to men but also to women undergoing cystectomy.