SYNTHESES OF ANOMERIC PAIRS OF NEW C-NUCLEOSIDES VIA 1,3-DIPOLAR CYCLOADDITION REACTION .1.

Authors
MAQBOOL Z HASAN M POTT KT MALIK A NIZAMI TA VOELTER W
Citation
Z. Maqbool et al., SYNTHESES OF ANOMERIC PAIRS OF NEW C-NUCLEOSIDES VIA 1,3-DIPOLAR CYCLOADDITION REACTION .1., Zeitschrift fur Naturforschung. B, A journal of chemical sciences, 52(11), 1997, pp. 1383-1392
Citations number
26
Journal title
Zeitschrift fur Naturforschung. B, A journal of chemical sciences → ACNP
ISSN journal
09320776
Volume
52
Issue
11
Year of publication
1997
Pages
1383 - 1392
Database
ISI
SICI code
0932-0776(1997)52:11<1383:SOAPON>2.0.ZU;2-A
Abstract
A convenient pathway to a variety of beta- and alpha-C-nucleosides has been developed by utilizing 1,3-dipolar cycloaddition reactions of va rious exocyclic and endocyclic heterocyclic ylides with beta (5a) and alpha (5b) anomers of ethyl ',3'-O-isopropylidene-5'-O-trityl-D-ribofu ranosyl) propiolate, respectively. Assignment of configuration at C-1' position of the C-nucleosides could be made by a comparative study of the properties of corresponding alpha and beta anomers with a reasona ble degree of certainity.