ECONOMICAL SPRAY-COATING OF HISTOLOGIC SLIDES WITH POLY-L-LYSINE

Coating both sides of histologic slides with poly-L-lysine (PLL) by th e conventional immersion technique is relatively costly and time-consu ming. We have devised and successfully employed a new method in which only the face side of the histologic slide is sprayed with PLL. We hav e compared the quality, reproducibility, and time and costs incurred o f our method with those of conventional techniques. Spray-coating of o nly 1 side of histologic slides with PLL is simple, and economical and renders as good quality as the expensive and time-consuming conventio nal methods.