Background In a ''case-control'' study we investigated the correl lati
ons among twenty-four clinical signs of ''functional impairment'' and
probability of ''activity daily living insufficiency''. Methods. The s
tudy involved 788 randomised inpatients, aged 65 years and over, of ni
neteen long-stay hospitals of an Italian region (Lazio, Rome), We meas
ured self care autonomy, mobility and continence, on a modified Barthe
l's scale; the score on Barthel's scale, Barthel Index (BI), was corre
lated to twenty-four signs of ''functional impairment'' (explicative v
ariables), Of these variables entered in stepwise regression only ''co
gnitive impairment'' (coef. B-22), ''paralysis'' (coef. B-21), ''body
weight reduction over 10 kg vs ideal weight'' (coef. B-12), ''joint de
formation'' (coef. B-7) and ''visual impairment'' (coef. B-5), Insuffi
ciency in daily living is defined by BI<100. The presence of these fiv
e clinical signs leads to the likelihood of ''activity dally living in
sufficiency'' to 0.996, The trend of cognitive impairment to rise with
age could be responsible for the inverse regression between age and B
I, Results, There was no significant correlation between BI and sex, H
earing impairment, serum creatinine level greater than or equal to 4 m
g/dl, bronchospasm, obstructive and restrictive ventilation disorders,
precordial pain on stress or spontaneous and dyspnea are not signific
antly correlated to the Barthel Index Score and to the likelihood of i
nsufficiency in daily living activity.