G. Buchkremer et al., PSYCHOEDUCATIONAL PSYCHOTHERAPY FOR SCHIZOPHRENIC-PATIENTS AND THEIR KEY RELATIVES OR CAREGIVERS - RESULTS OF A 2-YEAR FOLLOW-UP, Acta psychiatrica Scandinavica, 96(6), 1997, pp. 483-491
Psychoeducational medication management training (PMT), cognitive psyc
hotherapy (CP) and key-person counselling (KC) were carried out in var
ious combinations in this randomized, controlled intervention study of
schizophrenic out-patients (according to DSM-III-R). Special design c
haracteristics of the study were a control group consisting of non-spe
cifically treated patients and a 2-year follow-up after completion of
treatment in order to evaluate medium-term effects. A total of 132 pat
ients underwent a follow-up examination 2 years after completion of tr
eatment and were evaluated with an intention-to-treat approach. In the
second follow-up year, ail treatment groups had lower but not signifi
cantly different relapse rates compared to the control group. The most
intensive treatment (PMT+CP+KC) produces a clinically relevant reduct
ion in rehospitalization rate (a 26% reduction compared to the control
group). In comparison with the non-specifically treated control group
, whose original effect decreased, at least a medium-term therapeutic
effect was recorded in the treatment groups.