Objective. To compare the clinical effect of breastfeedings and bottle
feedings in extremely low birth weight (ELBW) infants (birth weight 8
00 g). Methods. A total of 12 ELBW infants (mean birth weight, 672 +/-
95 g; mean gestation, 26 +/- 2 weeks) served as their own controls in
this prospective study comparing physiologic parameters during bottle
and breastfeeding. The infants were put to breast the same week they
began on bottle feedings of human milk or premature infant formula (me
an gestation, 35 weeks). One breastfeeding and one bottle feeding were
observed each day for 10 days. Pre-and postfeeding weights were measu
red, and oxygen saturation, respiratory rate, heart rate, and axillary
temperature were monitored continuously and recorded every minute dur
ing feedings. Results. The infants demonstrated a higher oxygen satura
tion and a higher temperature during breastfeeding than during bottle
feeding, and were less likely to desaturate to <90% oxygen during brea
stfeeding. Mean weight gain was greater during bottle feeding than dur
ing breastfeeding (31 vs 9 g). Conclusions. Breastfeeding the ELBW inf
ant is desirable from a standpoint of improved physiologic responses,
but such practice requires breastfeeding support and possible suppleme
ntation to optimize weight gain.