USE OF INTEGRAL AND DIFFERENTIAL METHODS FOR THE DETERMINATION OF L-DOPA IN PURE FORM AND PHARMACEUTICAL PREPARATIONS

Authors
HELALEH MIH RAHMAN N JAMHOUR RMAQ ABUNAMEH ESM
Citation
Mih. Helaleh et al., USE OF INTEGRAL AND DIFFERENTIAL METHODS FOR THE DETERMINATION OF L-DOPA IN PURE FORM AND PHARMACEUTICAL PREPARATIONS, Journal of pharmaceutical and biomedical analysis, 16(2), 1997, pp. 269-274
Citations number
19
Journal title
Journal of pharmaceutical and biomedical analysis → ACNP
ISSN journal
07317085
Volume
16
Issue
2
Year of publication
1997
Pages
269 - 274
Database
ISI
SICI code
0731-7085(1997)16:2<269:UOIADM>2.0.ZU;2-V
Abstract
A new simple and selective kinetic method for the determination of L-d opa, using differential and integral methods, is described. The spectr ophotometric measurements were recorded by measuring the increase in a bsorbance at 300 nm. The concentration range was valid from 5-35 ppm. The complex ratio showed a (1:2) of L-dopa with respect to sodium hydr oxide, with formation constant 5.06 x 10(6) and molar absorptivity of 3.85 x 10(3) 1 mol(-1) cm(-1). (C) 1997 Elsevier Science B.V.