ENANTIOSELECTIVE SYNTHESIS OF FLAVONOIDS .3. TRANS-FLAVAN-3-OL AND CIS-FLAVAN-3-OL METHYL-ETHER ACETATES

Authors
VANRENSBURG H VANHEERDEN PS FERREIRA D
Citation
H. Vanrensburg et al., ENANTIOSELECTIVE SYNTHESIS OF FLAVONOIDS .3. TRANS-FLAVAN-3-OL AND CIS-FLAVAN-3-OL METHYL-ETHER ACETATES, Journal of the Chemical Society. Perkin transactions. I, (22), 1997, pp. 3415-3421
Citations number
23
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
22
Year of publication
1997
Pages
3415 - 3421
Database
ISI
SICI code
0300-922X(1997):22<3415:ESOF.T>2.0.ZU;2-G
Abstract
Asymmetric dihydroxylation of a series of polyoxygenated 1,3-diarylpro penes with AD-mix-alpha or AD-mix-beta in the presence of methanesulfo namide and subsequent acid-catalysed cyclization, affords for the firs t time synthetic access to trans- and cis-flavan-3-ol derivatives, ess entially enantiopure and in good yield.