Jc. Mansfield et al., OPEN ACCESS GASTROSCOPY FINDINGS ARE UNRELATED TO THE USE OF ASPIRIN AND NONSTEROIDAL ANTIINFLAMMATORY DRUGS, British journal of general practice, 47(425), 1997, pp. 825-826
This study aims to determine whether priority should be given to patie
nts taking non-steroidal anti-inflammatroy drugs (NSAIDs) or aspirin w
hen selecting which dyspeptic patients to refer for open access gastro
scopy. A total of 8156 patients underwent gastroscopy, all of whom had
upper gastrointestinal symptoms. Patients taking NSAIDs or aspirin sh
owed no significant differences in the frequency of ulcer disease when
age-matched groups were compared. Although NSAIDs and aspirin are fre
quently implicated in gastrointestinal bleeding in the elderly, patien
ts referred for investigation of dyspepsia show no increase in major e
ndoscopic pathology.