A SIMPLIFIED SYNTHESIS OF (+ -)-1,2-DIPHENYL-1,2-DIAMINOETHANE (1) FROM BENZALDEHYDE AND AMMONIA - REVISION OF THE STRUCTURES OF THE LONG-KNOWN INTERMEDIATES HYDROBENZAMIDE AND AMARINE/
Ej. Corey et Fnm. Kuhnle, A SIMPLIFIED SYNTHESIS OF (+ -)-1,2-DIPHENYL-1,2-DIAMINOETHANE (1) FROM BENZALDEHYDE AND AMMONIA - REVISION OF THE STRUCTURES OF THE LONG-KNOWN INTERMEDIATES HYDROBENZAMIDE AND AMARINE/, Tetrahedron letters, 38(50), 1997, pp. 8631-8634
A new pathway for the simple, stereocontrolled and economical synthesi
s of (+/-)-1 from benzaldehyde is described. The structures of two int
ermediates (Scheme 1) have been revised to those shown in Scheme 2. (C
) 1997 Elsevier Science Ltd.