The control of ventilatory responses to mild or moderate dynamic exerc
ise has been the subject of considerable debate for over a century. Th
e prevailing view has been that the ventilatory response to exercise i
s stereotypical and rather unmalleable. However, paradigms involving n
ovel associations of stimulus inputs have been shown to modulate breat
hing in short and longer time scales. The scope of this review include
s examples of modified ventilatory responses to exercise which have be
en investigated in terms of neural mechanisms. An attempt to synthesis
e the available data into a model of neuromodulation is presented. (C)
1997 Elsevier Science B.V.