The case is described of a 58 year old man with systemic Whipple's dis
ease with pericardial and pleural effusions and severe pulmonary hyper
tension. After three months of antibiotic treatment there was a comple
te resolution, not only of the symptoms known to be associated with Wh
ipple's disease (diarrhoea, arthralgia, pericardial and pleural effusi
ons), but also of pulmonary hypertension.