Eh. Snell et al., CCD VIDEO OBSERVATION OF MICROGRAVITY CRYSTALLIZATION OF LYSOZYME ANDCORRELATION WITH ACCELEROMETER DATA, Acta crystallographica. Section D, Biological crystallography, 53, 1997, pp. 747-755
Lysozyme has been crystallized using the ESA Advanced Protein Crystall
ization Facility onboard the NASA Space Shuttle Orbiter during the IML
-2 mission. CCD video monitoring was used to follow the crystallizatio
n process and evaluate the growth rate. During the mission some tetrag
onal crystals were observed moving over distances of up to 200 mu m. T
his was correlated with microgravity disturbances caused by firings of
vernier jets on the Orbiter. Growth-rate measurement of a stationary
crystal (which had nucleated on the growth reactor wall) showed spurts
and lulls correlated with an onboard activity: astronaut exercise. Th
e stepped growth rates may be responsible for the residual mosaic bloc
k structure seen in crystal mosaicity and topography measurements.