A. Abusafieh et al., DEVELOPMENT OF SELF-ANCHORING BONE IMPLANTS .1. PROCESSING AND MATERIAL CHARACTERIZATION, Journal of biomedical materials research, 38(4), 1997, pp. 314-327
We recently designed and produced a family of new swelling-type materi
als that are potentially capable of self-fixation in bone. These mater
ials are designed to absorb body fluids and swell by small amounts, wh
ich will allow the implants made from these materials to achieve self-
fixation by an expansion-fit mechanism. The developed material system
is essentially a crosslinked random copolymer based on poly(methyl met
hacrylate-acrylic acid). For potential structural (load-bearing) bioim
plant applications, we reinforced this copolymer with AS-4 carbon and
Kevlar 49 fibers. The details of processing these materials and the st
eps involved in optimizing their microstructures are presented in this
article. A set of mechanical tests were performed on these materials
in both dry and swollen conditions to measure their moduli and yield s
trengths. In the dry state, the copolymers were found to exhibit Young
's moduli in the range of 3 to 4 GPa and yield strengths in the range
of 70 to 85 MPa. The reinforced composites exhibited moduli in the ran
ge of 15 to 65 GPa and yield strengths in the range of 125 to 500 MPa.
Upon controlling the volumetric swelling in these materials to be les
s than about 10%, the loss in mechanical properties was found to be le
ss than about 30%. These hygromechanical properties are well suited fo
r self-anchoring bone implant applications. (C) 1997 John Wiley & Sons
, Inc.