TRANSESTERIFICATION BETWEEN ACETYLATED AND FREE CARBOHYDRATES

Transesterification reactions have been performed in systems in which both acyl acceptor and acyl donor are carbohydrates with the same skel eton. Basic catalysis proved to be much more efficient than nucleophyl ic catalysis. Partially acetylated sugar derivatives have been prepare d by selective deacylation of peracetylated glycosides, using transest erification between a peracetylated sugar and a non-protected carbohyd rate. This method compares favourably with known regioselective acylat ion methods.