K. Balasandaram et al., BIOELECTRICAL ACTIVITY OF BRAIN IN RANA-TIGRINA (DAUDIN) IN RESPONSE TO PHOSALONE POISONING, Comparative biochemistry and physiology. C. Comparative pharmacologyand toxicology, 118(2), 1997, pp. 229-231
An acute dose of phosalone, intraperitoneally injected to Rana tigrina
alters the bioelectrical activity of the brain. The frequency levels
of delta, theta, alpha, and beta waves remained similar in both contro
l and experimental groups, while the amplitude of the waves was signif
icantly decreased by 40 to 60% in the latter group. The total work don
e (TWD) was also significantly reduced. The above disturbance in the b
rain electrical activity may have correlation to the inhibition of cat
ion-linked ATPase, as well as the cholinesterase activity. (C) 1997 El
sevier Science Inc.