O. Gauthier et al., BIOMATERIALS FOR BONE SUBSTITUTION AND BO NE ALLOGRAFTS - COMPARED STUDY IN FULL WEIGHT-BEARING CONDITIONS, Revue de Medecine Veterinaire, 148(10), 1997, pp. 813-821
Three different bone substitutes were used to fill an important femora
l diaphyseal defect. Eighteen implantations were performed on 10 beagl
e dogs, with interlocked intramedullary nailing. 83 % of the implantat
ions gave very good functionnal results whatever the bone substitute.
Radiologically and histologically, substitutes made of hydroxyapatite
and polymethylmethacrylate were never successful. With efficient stabi
lisation with four interlocking screws, biphasic calcium phosphate cer
amics showed better healing process than cortical allografts and expre
ssed their interesting biological properties and their ability to supp
ort weight-bearing conditions.