Wd. Creery et al., SURFACTANT THERAPY IMPROVES PULMONARY-FUNCTION IN INFANTS WITH PNEUMOCYSTIS-CARINII PNEUMONIA AND ACQUIRED-IMMUNODEFICIENCY-SYNDROME, Pediatric pulmonology, 24(5), 1997, pp. 370-373
Pneumocystis carinii pneumonia (PCP) is an important cause of acute re
spiratory failure in HIV-infected children. PCP may initiate acute res
piratory distress syndrome (ARDS) by adversely affecting surfactant ph
ysiology. We report improved pulmonary function following administrati
on of bovine lipid extract surfactant to two infants with AIDS-related
PCP/ARDS. (C) 1997 Wiley-Liss, Inc.