Df. Zatzick et al., POSTTRAUMATIC-STRESS-DISORDER AND FUNCTIONING AND QUALITY-OF-LIFE OUTCOMES IN A NATIONALLY REPRESENTATIVE SAMPLE OF MALE VIETNAM VETERANS, The American journal of psychiatry, 154(12), 1997, pp. 1690-1695
Objective: Although posttraumatic stress disorder (PTSD) is a highly p
revalent and often chronic condition, the relationship between PTSD an
d functioning and quality of life remains incompletely understood. Met
hod: The authors undertook an archival analysis of data front the Nati
onal Vietnam Veterans Readjustment Study. The study subjects consisted
of the nationally representative sample of male Vietnam veterans who
participated in the National Vietnam Veterans Readjustment Study. The
authors estimated PTSB at the time of the interview with the Mississip
i Scale for Combat-Related Posttraumatic Stress Disorder. They examine
d the following outcomes: diminished well-being, physical limitations,
bed day in the past 2 weeks, compromised physical health status, curr
ently not working, and perpetration of violence. Logistic models were
used to determine the association between PTSD and outcome; adjustment
was made for demographic characteristics and comorbid psychiatric and
other medical conditions. Results: The risks of poorer outcome were s
ignificantly higher in subjects with PTSD than in subjects without PTS
D in five of the six domains. For the outcome domains of physical limi
tations, not working, compromised physical health, and diminished well
-being, these significantly higher risks persisted even in the most co
nservative logistic models that removed the shared effects of comorbid
psychiatric and other medical disorders. Conclusions: The suffering a
ssociated with combat related-PTSD extends beyond the signs and sympto
ms of the disorder to broader areas of functional and social morbidity
. The significantly higher risk of impaired functioning and diminished
quality of life uniquely attributable to PTSD suggests that PTSD may
well be the core problem in this group of difficult to treat and multi
ply afflicted patients.