FLUORO ORGANICS - FACILE SYNTHESES OF NOVEL 2-TRIFLUOROMETHYL-1H-ARYLO-1,5-DIAZEPINES OR 4-TRIFLUOROMETHYL-1H-ARYLO-1,5-DIAZEPINES, OXAZEPINES, THIAZEPINES, 2-(1,1,1-TRIFLUOROACETONYL)IMIDAZOLES, OXAZOLES AND THIAZOLES

Authors
REDDY ACS RAO PS VENKATARATNAM RV
Citation
Acs. Reddy et al., FLUORO ORGANICS - FACILE SYNTHESES OF NOVEL 2-TRIFLUOROMETHYL-1H-ARYLO-1,5-DIAZEPINES OR 4-TRIFLUOROMETHYL-1H-ARYLO-1,5-DIAZEPINES, OXAZEPINES, THIAZEPINES, 2-(1,1,1-TRIFLUOROACETONYL)IMIDAZOLES, OXAZOLES AND THIAZOLES, Tetrahedron, 53(16), 1997, pp. 5847-5854
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
16
Year of publication
1997
Pages
5847 - 5854
Database
ISI
SICI code
0040-4020(1997)53:16<5847:FO-FSO>2.0.ZU;2-6
Abstract
Exclusive formation of either 2- or 4-trifluoromethyl(1H,5)arylodiazep ines (5,7)/(6,8) was observed in the condensation of 1,1,1-trifloro-3- (isobutoxymethylene)-2-propanones 2/3 with o-arylenediamines 4 under m icrowave irradiation conditions. Thermal reactions under the same temp erature and time produced no products. Orthoaminophenols 9 and o-amino thiophenol 12 with 2 and 3 under the same conditions produced the resp ective oxazepines 10,11 and thiazepines 13,14. The. synthetic equvalen t 1 gave similarly benzimidazoles 15, benzoxazoles 16 and benzthiazole s 17. (C) 1997 Elsevier Science Ltd.