STRUCTURE AND CONFORMATION OF THE PROCYANIDIN B-2 DIMER

Authors
KHAN ML HASLAM E WILLIAMSON MP
Citation
Ml. Khan et al., STRUCTURE AND CONFORMATION OF THE PROCYANIDIN B-2 DIMER, Magnetic resonance in chemistry, 35(12), 1997, pp. 854-858
Citations number
25
Categorie Soggetti
Spectroscopy,Chemistry
Journal title
Magnetic resonance in chemistry → ACNP
ISSN journal
07491581
Volume
35
Issue
12
Year of publication
1997
Pages
854 - 858
Database
ISI
SICI code
0749-1581(1997)35:12<854:SACOTP>2.0.ZU;2-1
Abstract
The structure of the proanthocyanidin B-2 dimer was proved to be (-)ep icatechin-(4 beta-8)-(-)epicatechin by two-dimensional heteronuclear N MR spectroscopy. The compound adopts two conformations in solution, in which the interflavan dihedral angles are roughly +/- 90 degrees. The preferred conformation of the pyran ring is a half-chair with the 3', 4'-dihydroxyphenyl substituents in pseudo-equatorial positions. (C) 19 97 John Wiley & Sons, Ltd.