Infection is infrequent after open fractures of the upper extremity. T
reatment begins with prevention through the appropriate use of prophyl
actic antibiotics, adequate wound debridement, and timely soft-tissue
coverage. If infection supervenes, the surgeon must identify the respo
nsible bacteria and administer antibiotics accordingly. Stable fixatio
n is retained. Unstable fixation is removed and skeletal stability res
tored. Using these principles, infection in the presence of skeletal f
ixation can be controlled and fracture union achieved.