NEW DELTA-AMINOALCOHOL FOR THE ENANTIOSELECTIVE ADDITION OF DIALKYLZINCS TO ALDEHYDES

Authors
GENOV M DIMITROV V IVANOVA V
Citation
M. Genov et al., NEW DELTA-AMINOALCOHOL FOR THE ENANTIOSELECTIVE ADDITION OF DIALKYLZINCS TO ALDEHYDES, Tetrahedron : asymmetry, 8(22), 1997, pp. 3703-3706
Citations number
27
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
22
Year of publication
1997
Pages
3703 - 3706
Database
ISI
SICI code
0957-4166(1997)8:22<3703:NDFTEA>2.0.ZU;2-A
Abstract
A new optically active delta-aminoalcohol has been synthesized diaster eoselectively in one step from (-)-menthone and N,N-dimethylaminopropy l lithium. The aminoalcohol catalyzed the addition of diethylzinc and dimethylzinc to aldehydes in high yields and enantioselectivities of u p to 89%. (C) 1997 Elsevier Science Ltd.