TRIAZOLE CARBOXYLIC-ACIDS AS ANIONIC SUGAR MIMICS - INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A D-GLUCOTRIAZOLE CARBOXYLATE

Authors
KRULLE T DELAFUENTE C PICKERING L APLIN RT TSITSANOU KE ZOGRAPHOS SE OIKONOMAKOS NG NASH RJ GRIFFITHS RC FLEET GWJ
Citation
T. Krulle et al., TRIAZOLE CARBOXYLIC-ACIDS AS ANIONIC SUGAR MIMICS - INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A D-GLUCOTRIAZOLE CARBOXYLATE, Tetrahedron : asymmetry, 8(22), 1997, pp. 3807-3820
Citations number
32
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
22
Year of publication
1997
Pages
3807 - 3820
Database
ISI
SICI code
0957-4166(1997)8:22<3807:TCAASM>2.0.ZU;2-E
Abstract
Triazole-carboxylic acids related to D-glucose and D-galactose may be prepared by intramolecular [1,3]-dipolar cycloadditions of azides to u nsaturated esters, followed by bromine oxidation of the resulting tria zoline. Such materials may provide a series of anionic mimics of carbo hydrates. (C) 1997 Elsevier Science Ltd.