S. Ghosal et al., HUMUS, THE EPITOME OF AYURVEDIO-MAKSHIKA, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 36(7), 1997, pp. 596-604
Ayurvedio makshika, a maharasa (rejuvenator, adaptogen), has been show
n to be constituted of a large number of low M-r (mol. wt) humio inter
mediates, and medium and high M-r humio compounds. These results dispe
l a long standing misbelief that the bioactive ingredients of makshika
constitute only inorganic minerals, viz. iron and chalco-pyrites. The
stability of the makshika-humus core (str 5) appears to be due to com
plexation with transition metal ions which produce resonance stabilise
d metalloorganic species (str 6a,b and 7). The low M-r organic compoun
ds of makshika, in their natural habitats, find ecological niche withi
n the micropores of humus and thereby fend off weathering and other ex
tranuous onslaughts for ages. Humus seems to be not one but of all mah
arasas' epitome. The general features of makshika and shilajit are com
pared in the light of their origin and biological significance.