CONVENIENT AND VERSATILE SYNTHETIC METHODS FOR FURAZANO[3,4-D]PYRIMIDINES

Authors
SAKO M ODA S HIROTA K BEARDSLEY GP
Citation
M. Sako et al., CONVENIENT AND VERSATILE SYNTHETIC METHODS FOR FURAZANO[3,4-D]PYRIMIDINES, Synthesis, (11), 1997, pp. 1255-1257
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
11
Year of publication
1997
Pages
1255 - 1257
Database
ISI
SICI code
0039-7881(1997):11<1255:CAVSMF>2.0.ZU;2-1
Abstract
Treatment of the readily available 6-amino-5-nitrosopyrimidines with a slight excess of iodobenzene diacetate or N-iodosuccinimide in anhydr ous DMF containing three equivalents of lithium hydride at ambient tem perature resulted in the smooth and versatile formation of the corresp onding furazano[3,4-d]pyrimidines, which are useful intermediates for the preparation of biologically interesting fused pyrimidines.