C. Medson et al., THE STEREOSELECTIVE PREPARATION OF BETA-HYDROXY ESTERS USING A YEAST REDUCTION IN AN ORGANIC-SOLVENT, Tetrahedron : asymmetry, 8(7), 1997, pp. 1049-1054
A range of (S)-beta-hydroxy esters has been prepared in high yield (56
-96%) and with very high enantioselectivity (>94%) using a yeast media
ted reduction in light petroleum. It was found that the ester function
ality had a marked effect on both the isolated yield and the quantity
of yeast required to effect complete reduction. (C) 1997 Elsevier Scie
nce Ltd.