2ND-GENERATION SYNTHESIS OF THE QUARTROMICIN SPIROTETRONIC ACID SUBUNITS VIA A CLAISEN REARRANGEMENT INTRAMOLECULAR ALDOL SEQUENCE

Authors
ROUSH WR BARDA DA
Citation
Wr. Roush et Da. Barda, 2ND-GENERATION SYNTHESIS OF THE QUARTROMICIN SPIROTETRONIC ACID SUBUNITS VIA A CLAISEN REARRANGEMENT INTRAMOLECULAR ALDOL SEQUENCE, Tetrahedron letters, 38(51), 1997, pp. 8785-8788
Citations number
27
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
51
Year of publication
1997
Pages
8785 - 8788
Database
ISI
SICI code
0040-4039(1997)38:51<8785:2SOTQS>2.0.ZU;2-N
Abstract
Spirotetronate 4 needed for the assignment of stereochemistry to the q uartromicins has been synthesized from 9 and 10 by a route featuring a Claisen rearrangement and intramolecular aldol reaction to establish the stereochemistry of the carbon framework. (C) 1997 Elsevier Science Ltd.