A MILD AND HIGHLY SELECTIVE N-BENZOYLATION OF CYTOSINE AND ADENINE BASES IN NUCLEOSIDES WITH N-BENZOYLTETRAZOLE

Authors
BHAT B SANGHVI YS
Citation
B. Bhat et Ys. Sanghvi, A MILD AND HIGHLY SELECTIVE N-BENZOYLATION OF CYTOSINE AND ADENINE BASES IN NUCLEOSIDES WITH N-BENZOYLTETRAZOLE, Tetrahedron letters, 38(51), 1997, pp. 8811-8814
Citations number
26
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
51
Year of publication
1997
Pages
8811 - 8814
Database
ISI
SICI code
0040-4039(1997)38:51<8811:AMAHSN>2.0.ZU;2-9
Abstract
N-Benzoyltetrazole has been developed as a mild and selective reagent for monobenzoylation of the exocyclic amino group in nucleic acid base s. its usefulness is demonstrated by protection of adenine and cytosin e bases, an important procedure in the nucleic acid chemistry field. ( C) 1997 Elsevier Science Ltd.