SYNTHESIS OF ,6,7-TETRADEOXY-2,6-IMINO-D-GLYCERO-D-IDO-HEPTITOL BY INTRAMOLECULAR AMINATION OF AZIRIDINE RING

Authors
CHAKRABORTY TK JAYAPRAKASH S
Citation
Tk. Chakraborty et S. Jayaprakash, SYNTHESIS OF ,6,7-TETRADEOXY-2,6-IMINO-D-GLYCERO-D-IDO-HEPTITOL BY INTRAMOLECULAR AMINATION OF AZIRIDINE RING, Tetrahedron letters, 38(51), 1997, pp. 8899-8902
Citations number
19
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
51
Year of publication
1997
Pages
8899 - 8902
Database
ISI
SICI code
0040-4039(1997)38:51<8899:SO,BI>2.0.ZU;2-K
Abstract
A novel intramolecular 6-exo opening of a terminal Boc-protected aziri dine ring by a strategically located amino group in the molecule enact ed the crucial cyclisation to furnish the key intermediate 10 with req uisite deoxyamino imino sugar framework leading to the stereoselective synthesis of -tetradeoxy-2,6-imino-D-glycero-D-ido-heptitol(5). (C) 1 997 Elsevier Science Ltd.