Ka. Marill et al., ANALYSIS OF THE TREATMENT OF SPONTANEOUS SUSTAINED STABLE VENTRICULAR-TACHYCARDIA, Academic emergency medicine, 4(12), 1997, pp. 1122-1128
Objectives: To determine the termination rate of spontaneous sustained
stable ventricular tachycardia (SSSVT) as a function of the first and
second therapeutic interventions used, and to determine factors assoc
iated with successful termination. Methods: A multihospital, retrospec
tive analysis of the treatment of patients with SSSVT was performed, T
he setting included 2 urban county hospitals, 2 urban private hospital
s, and a Veterans Affairs hospital, Cases were identified by discharge
diagnosis and ECG characteristics, and confirmed by electrophysiology
study or ECG criteria, Results: There were 40 cases of SSSVT identifi
ed, Excluding adenosine, 35 patients were treated with lidocaine as a
first intervention. The rate of termination with lidocaine bolus was 1
7% (6 of 35) (95% CT 7-34%), Regarding the 35 patients initially treat
ed with lidocaine, the odds of termination of SSSVT were 11 times grea
ter in those without a history of previous myocardial infarction (MI)
than in those with a history of MI (95% CI 0.96-551), Of the 29 patien
ts who failed initial lidocaine treatment, 23 were treated with a seco
nd lidocaine bolus, with a termination rate of 18% (4 of 22) (95% CI 5
-40%), Only 2 patients with sustained ventricular tachycardia had a co
ncurrent MI, and the tachycardia was unresponsive to initial lidocaine
bolus in both cases. Fifteen patients received adenosine with no tach
ycardia terminations and no significant adverse effects, Conclusions:
The rate of SSSVT termination with lidocaine was low, particularly in
patients with a history of MI.